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At the same time, the CD spectrum of 1 NF in the Soret region displayed a strong negative peak at 380 nm and a positive peak at 426 nm, indicating tightly packed neighboring porphyrins 32,33

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ETHICS APPROVAL AND CONSENT TO PARTICIPATE All animal experiments were conducted in strict accordance with the Guidelines for the Care and Use of Laboratory Animals of Naval Medical University, China, and approved by the Animal Ethics Committee of Naval Medical University

Testa B, Testa D, Mesolella M, DErrico G, Tricarico D, Motta G

The reduction of human RNR, which was suggested to follow mechanism (ii) 46 , therefore needs to be analyzed and monothiol mechanism (iii) should be also considered